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PC3 prostate tumor-initiating cells with molecular profile FAM65Bhigh/MFI2low/LEF1low increase tumor angiogenesis.
Zhang K, Waxman DJ. Zhang K, et al. Mol Cancer. 2010 Dec 29;9:319. doi: 10.1186/1476-4598-9-319. Mol Cancer. 2010. PMID: 21190562 Free PMC article.
The PC3 holoclones did not show significant enriched expression of the putative prostate cancer stem cell markers CD44 and integrin alpha2beta1. PC3 tumors seeded with holoclones showed dramatic down regulation of FAM65B and dramatic up regulation of MFI2 and LEF1, …
The PC3 holoclones did not show significant enriched expression of the putative prostate cancer stem cell markers CD44 and integrin a …
Discovery of a Highly Conserved Peptide in the Iron Transporter Melanotransferrin that Traverses an Intact Blood Brain Barrier and Localizes in Neural Cells.
Singh CSB, Eyford BA, Abraham T, Munro L, Choi KB, Okon M, Vitalis TZ, Gabathuler R, Lu CJ, Pfeifer CG, Tian MM, Jefferies WA. Singh CSB, et al. Front Neurosci. 2021 Jun 2;15:596976. doi: 10.3389/fnins.2021.596976. eCollection 2021. Front Neurosci. 2021. PMID: 34149342 Free PMC article.
Our previous studies demonstrated that that a soluble form of melanotransferrin (MTf; Uniprot P08582; also known as p97, MFI2, and CD228), a mammalian iron-transport protein, is an effective carrier for delivery of drug conjugates across the BBB into the brain and was the …
Our previous studies demonstrated that that a soluble form of melanotransferrin (MTf; Uniprot P08582; also known as p97, MFI2, and CD …